Efficacy and Safety of Sodium Picosulfate/Magnesium Citrate for Bowel Preparation in a Physically Disabled Outpatient Population: A Randomized, Endoscopist-Blinded Comparison With Ascorbic Acid-Enriched Polyethylene Glycol Solution Plus Bisacodyl (The PICO-MOVI Study).

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

This study aimed to compare a small-volume sodium picosulfate/magnesium citrate preparation with a 2-L ascorbic acid-enriched polyethylene glycol solution plus bisacodyl.

Why It Was Studied

Because of its volume, adequate bowel preparation remains problematic in physically unfit patients.

These results in a physically disabled ambulant population cannot be extrapolated to immobile, hospitalized patients.

Who Took Part

The study group was 146 patients.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

This study was conducted in an outpatient department.

Patients referred for diagnostic colonoscopy were randomly assigned.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Key exclusion criteria were severe kidney disease, ASA class ≥III, and hospital admission.

Patients in the sodium picosulfate/magnesium citrate group received advice on the recommended 4-L fluid intake.

Patients in the ascorbic acid-enriched polyethylene glycol solution plus bisacodyl group received 2 bisacodyl tablets 2 days before and advice on the additionally recommended 2-L fluid intake.

What Was Measured

The subject headings attached to it are Ascorbic Acid, Awareness, Bisacodyl, Cathartics, Citrates, Citric Acid and Colonic Neoplasms.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 146 patients.

Its findings take up roughly 12 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (Diseases of the colon and rectum), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.