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Scottsdale Magnesium Study: Absorption, Cellular Uptake, and Clinical Effectiveness of a Timed-Release Magnesium Supplement in a Standard Adult Clinical Population.

Plain-language guide to PMID 29425476 (2018): placebo-controlled pragmatic clinical trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 91 adults, cellulite.

Key Facts

PMID
29425476
Journal
Journal of the American College of Nutrition
Year
2018
Study type
Pragmatic Clinical Trial
Authors
Weiss D et al. (3 authors)
DOI
10.1080/07315724.2017.1398686

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in the context of cellulite in this pragmatic clinical trial publication.

Therapeutically addressing magnesium status can be challenging, as higher supplementation often leads to bowel intolerance.

Who Took Part

The abstract describes 91 adults taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

How the Study Was Run

The design is described as placebo-controlled.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

Baseline serum magnesium, red blood cell (RBC) magnesium, and magnesium status questionnaire scores were collected prior to trial initiation.

Both RBC magnesium and the magnesium status questionnaire were evaluated at 90 days.

What Was Measured

PubMed files the paper under topics including Diarrhea, Erythrocytes, Folic Acid, Magnesium, Placebo Effect, Surveys and Questionnaires and Vitamin B 12.

The authors tagged it with the keywords MagSRT™, Magnesium malate, magnesium status and timed-release.

What This Means in Plain Language

The paper is a placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 91 adults in people with cellulite.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2018 (Journal of the American College of Nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, Cellulite research.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.