The effect of zinc sulfate on prevention, incidence, and severity of mucositis in leukemia patients undergoing chemotherapy.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

This study aimed to evaluate the effect of zinc sulfate on the incidence and severity of mucositis in leukemia patients undergoing chemotherapy.

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

This study was conducted on leukemia patients undergoing chemotherapy.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

This was a randomized clinical trial and placebo-controlled, triple blinded study.

Mucositis was measured by the oral mucositis index and World Health Organization mucositis scale on the 4th, 7th, and 14th days after chemotherapy.

The data were analyzed using independent t-test, chi-square test, and Repeated Measures Analysis of Variance (RM-ANOVA).

What Was Measured

PubMed files the paper under topics including Analysis of Variance, Antineoplastic Agents, Astringents, Chi-Square Distribution, Incidence, Leukemia and Stomatitis.

The authors tagged it with the keywords Chemotherapy, Mucositis and Zinc sulfate.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (European journal of oncology nursing : the official journal of European Oncology Nursing Society), a journal based in Scotland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.