← Human Trials & Peer-Reviewed Studies

Effects of Different Dietary Interventions on Calcitriol, Parathyroid Hormone, Calcium, and Phosphorus: Results from the DASH Trial

Plain-language guide to PMID 29562597 (2018): randomized controlled trial study of Parathyroid Hormone (PTH 1-84) in 334 participants.

Key Facts

PMID
29562597
Journal
Nutrients
Year
2018
Study type
Randomized Controlled Trial
Authors
Hassoon A et al. (5 authors)
DOI
10.3390/nu10030367

What This Study Did, in Plain Language

What Was Tested

Researchers studied Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.

This secondary analysis of the DASH trial aimed to determine the effect of dietary patterns on blood concentrations of calcitriol, parathyroid hormone (PTH), ionized calcium, and urinary excretion of calcium and phosphorus.

Why It Was Studied

DASH's effect on calcitriol and other markers of bone-mineral metabolism is unknown.

Outcomes were available in 334 participants in the trial.

Who Took Part

According to the abstract, 334 participants were involved.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

After a 3-week run-in on the control diet, participants were randomized to control, fruits and vegetables (F&V), or DASH diets.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Parathyroid Hormone (PTH 1-84) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

A time span of 3 weeks appears in the methods.

Outcomes were assessed at the end of run-in, and during the last week of the intervention period.

What Was Measured

Outcomes were available in 334 participants in the trial.

The subject headings attached to it are Calcitriol, Calcium, Diet, Healthy, Dietary Approaches To Stop Hypertension, Feeding Behavior, Fruit and Parathyroid Hormone.

Author keywords: DASH trial and vitamin D.

What This Means in Plain Language

The paper is a randomized study of Parathyroid Hormone (PTH 1-84) in 334 participants over 3 weeks.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2018 (Nutrients), a journal based in Switzerland.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.

Our Notes on the Compound

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.