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Vitamin D deficiency and pre-eclampsia in Colombia: PREVitD study.
Plain-language guide to PMID 29588145 (2018): multicenter observational study of Vitamin D, K2, Magnesium and Zinc in 1013 women.
Key Facts
- PMID
- 29588145
- Journal
- Pregnancy hypertension
- Year
- 2018
- Study type
- Observational Study
- Authors
- Serrano NC et al. (7 authors)
- DOI
- 10.1016/j.preghy.2018.03.006
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.
Pre-eclampsia is a multisystem disorder characterized by new-onset hypertension and proteinuria during pregnancy.
Vitamin D has a very diverse biological role in cardiovascular diseases.
This study will evaluate the association of vitamin D levels and relevance to pre-eclampsia.
Who Took Part
The study group was 1013 women.
By PubMed's age tags, the people studied were teenagers, young adults and adults, women only.
The researchers conducted a case-control study of women recruited from the GenPE (Genetics and Pre-eclampsia) Colombian registry.
This is a multicenter case-control study conducted in eight Colombian cities. 25-Hydroxyvitamin D (25(OH)D) concentration was measured using liquid-chromatography-tandem mass spectrometry from 1013 women with pre-eclampsia and 1015 mothers without pre-eclampsia (controls).
How the Study Was Run
In design terms this was a multicenter study.
Running at several centres spread the Vitamin D, K2, Magnesium and Zinc study over different clinics and patient groups.
What Was Measured
The subject headings attached to it are Case-Control Studies, Causality, Colombia, Pre-Eclampsia, Registries, Risk Factors and Vitamin D.
The authors tagged it with the keywords Aetiology, Case-control study and Hypertensive disorders of pregnancy.
What This Means in Plain Language
The paper is a multicenter study of Vitamin D, K2, Magnesium and Zinc in 1013 women.
With several hundred people or more, it is a fairly large study for this kind of research.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2018 (Pregnancy hypertension), a journal based in Netherlands.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.