Correlation between serum vitamin B12 level and peripheral neuropathy in atrophic gastritis.

What Was Tested

Researchers studied Cyanocobalamin (Vitamin B12) in this observational study publication.

To explore the correlation between serum vitamin B12 level and peripheral neuropathy in patients with chronic atrophic gastritis (CAG).

Who Took Part

The abstract describes 593 patients taking part.

By PubMed's age tags, the people studied were young adults, adults, middle-aged adults and older adults, both men and women.

A total of 593 patients diagnosed with chronic gastritis by gastroscopy and pathological examination from September 2013 to September 2016 were selected for this study.

The age of these patients ranged within 18- to 75-years-old.

How the Study Was Run

Blood pressure, height and weight were measured in each patient, and the body mass index value was calculated.

Furthermore, gastric acid, serum gastrin, serum vitamin and serum creatinine tests were performed, and peripheral nerve conduction velocity and Helicobacter pylori (H. pylori) were detected.

In addition, the type of gastritis was determined by gastroscopy.

The above factors were used as independent variables to analyze chronic gastritis with peripheral neuropathy and vitamin B12 deficiency risk factors, and to analyze the relationship between vitamin B12 levels and peripheral nerve conduction velocity.

In addition, in the treatment of CAG on the basis of vitamin B12, patients with peripheral neuropathy were observed.

What Was Measured

Topics PubMed links to this paper include China, Folic Acid, Gastritis, Atrophic, Gastroscopy, Helicobacter Infections, Helicobacter pylori and Neural Conduction.

The authors tagged it with the keywords Chronic atrophic gastritis, Chronic gastritis, Peripheral neuropathy and Vitamin B12.

What This Means in Plain Language

This is an observational study of Cyanocobalamin (Vitamin B12) in 593 patients.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2018 (World journal of gastroenterology), a journal based in United States.

More context: the Cyanocobalamin (Vitamin B12) compound page, all human trials.