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Maternal vitamin D and markers of glycaemia during pregnancy in the Belfast centre of the Hyperglycaemia and Adverse Pregnancy Outcome study.

Plain-language guide to PMID 29608221 (2018): observational study of Vitamin D, K2, Magnesium and Zinc in 1585 women.

Key Facts

PMID
29608221
Journal
Diabetic medicine : a journal of the British Diabetic Association
Year
2018
Study type
Observational Study
Authors
Casey C et al. (7 authors)
DOI
10.1111/dme.13632

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.

To measure total 25-hydroxyvitamin D levels in women in mid-pregnancy who participated in the Belfast centre of the Hyperglycaemia and Adverse Pregnancy Outcome (HAPO) observational study, and to investigate the associations between levels of 25-hydroxyvitamin D and markers of gestational diabetes mellitus and lipid biomarkers.

Who Took Part

According to the abstract, 1585 women were involved.

The age groups tagged for this paper are teenagers, young adults and adults, women only.

A total of 1585 pregnant women had serum samples available for measurement.

Participants were recruited from the Royal Jubilee Maternity Hospital, Belfast, Northern Ireland, at 24-32 weeks' gestation, as part of the HAPO study. 25-hydroxyvitamin D concentrations were measured using liquid chromatography tandem mass spectrometry.

How the Study Was Run

Glucose, C-peptide and lipid levels were previously analysed in a central laboratory.

What Was Measured

PubMed files the paper under topics including 25-Hydroxyvitamin D 2, Blood Glucose, C-Peptide, Calcifediol, Cholesterol, Chromatography, Liquid and Diabetes, Gestational.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 1585 women.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (Diabetic medicine : a journal of the British Diabetic Association), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.