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Vitamin D supplementation in adolescents with irritable bowel syndrome: Is it useful? A randomized controlled trial.

Plain-language guide to PMID 29637918 (2018): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
29637918
Journal
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Year
2018
Study type
Randomized Controlled Trial
Authors
El Amrousy D et al. (5 authors)
DOI
10.4103/sjg.SJG_438_17

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Vitamin D deficiency is common in irritable bowel syndrome (IBS).

There is growing interest in the role of vitamin D in pediatric IBS.

The researchers aimed to evaluate the effect of vitamin D supplementation in adolescents with IBS and vitamin D deficiency.

Who Took Part

By PubMed's age tags, the people studied were teenagers, both men and women.

Vitamin D status as well as different IBS score systems (IBS-SSS, IBS-QoL, and total score) were evaluated before and 6 months after treatment.

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

One hundred and twelve adolescents with IBS and vitamin D deficiency were randomly divided into two groups of matched age and sex.

What Was Measured

PubMed files the paper under topics including Dietary Supplements, Irritable Bowel Syndrome, Vitamin D and Vitamin D Deficiency.

Author keywords: Adolescents.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2018 (Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association), a journal based in India.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.