The effect of initiating intravenous oxytocin infusion before uterine incision on the blood loss during elective cesarean section: a randomized clinical trial

What Was Tested

This randomized controlled trial paper looks at Oxytocin.

Objective: This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section (CS).

Why It Was Studied

The primary outcome was the mean volume of blood loss during CS.

Results: The baseline characteristics of both groups are quiet similar.

Who Took Part

The study group was 200 women.

The age groups tagged for this paper are young adults and adults, women only.

How the Study Was Run

The researchers set it up as a randomized and single-blind study.

The women were allocated by chance, so the Oxytocin group and the comparison group should start out alike.

Only one side, usually the women, was kept unaware of whether Oxytocin was given.

What Was Measured

The primary outcome was the mean volume of blood loss during CS.

The subject headings attached to it are Blood Loss, Surgical, Cesarean Section, Constriction, Elective Surgical Procedures, Oxytocin, Postpartum Hemorrhage and Pregnancy Outcome.

The authors tagged it with the keywords Atony and uterotonics.

What This Means in Plain Language

The paper is a randomized and single-blind study of Oxytocin in 200 women.

The publication is from 2019 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.

More context: the Oxytocin compound page, all human trials.