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Efficacy of oral vitamin D on glycated haemoglobin (HbA1c) in type 2 diabetics having vitamin D deficiency - A randomized controlled trial.

Plain-language guide to PMID 29885163 (2018): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 2 patients.

Key Facts

PMID
29885163
Journal
JPMA. The Journal of the Pakistan Medical Association
Year
2018
Study type
Randomized Controlled Trial
Authors
Khan DM et al. (5 authors)

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Blood samples of both the groups were tested for glycated haemoglobin at three months to assess the change.

Who Took Part

The study group was 2 patients.

The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.

This randomised control trial was carried out at Mayo Hospital, Lahore, from February 5 to August 5, 2016, and comprised type 2 diabetes patients aged 40-70 years visiting the outpatient clinics.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

They were randomly divided into two groups by using the lottery method.

Group A received oral vitamin D along with metformin and group B received metformin only.

SPSS 21 was used for data analysis.

What Was Measured

Topics PubMed links to this paper include Diabetes Mellitus, Type 2, Dietary Supplements, Glycated Hemoglobin, Hypoglycemic Agents, Metformin, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords Vitamin D, HbA1c, Diabetes mellitus, Type 2, Supplementation.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 2 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (JPMA. The Journal of the Pakistan Medical Association), a journal based in Pakistan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.