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Effect of magnesium sulfate on anesthesia depth, awareness incidence, and postoperative pain scores in obstetric patients. A double-blind randomized controlled trial.
Plain-language guide to PMID 29915852 (2018): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 100 women.
Key Facts
- PMID
- 29915852
- Journal
- Saudi medical journal
- Year
- 2018
- Study type
- Randomized Controlled Trial
- Authors
- Altıparmak B et al. (6 authors)
- DOI
- 10.15537/smj.2018.6.22376
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
To assess the effects of magnesium on the depth of anesthesia and to determine the effects of magnesium on incidence of awareness and postoperative pain after caesarean section.
Why It Was Studied
Methods: The study was designed as a double-blind, controlled, randomized study and conducted in Hacettepe University Hospital, Ankara, Turkey between January 2015 and March 2016.
After induction, sevoflurane was used for maintenance in Group S and desflurane in Group D (control groups).
Who Took Part
According to the abstract, 100 women were involved.
The age groups tagged for this paper are teenagers, young adults and adults, women only.
A total of 100 pregnant healthy women who were between 17 and 41 years old, ASA II, and scheduled for an elective cesarean section with general anesthesia were included in the study.
How the Study Was Run
The design is described as randomized and double-blind.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
What Was Measured
Bispectral index scores (BIS), fentanyl consumption and postoperative visual analogue scale (VAS) values were recorded.
Topics PubMed links to this paper include Adjuvants, Anesthesia, Anesthesia, General, Anesthesia, Obstetrical, Anesthetics, Inhalation, Cesarean Section, Consciousness Monitors and Desflurane.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 100 women.
The publication is from 2018 (Saudi medical journal), a journal based in Saudi Arabia.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.