Evaluation of nicotine patch in pain control of patients undergoing laparoscopic cholecystectomy

What Was Tested

This randomized controlled trial paper looks at Therapeutic nicotine (patch, non-peptide).

To analyze the effects of nicotine patch on pain control, occurrence of nausea and its hemodynamic repercussions in laparoscopic cholecystectomy procedures.

Who Took Part

The study group was 17 patients.

The age groups tagged for this paper are teenagers, young adults, adults and middle-aged adults, both men and women.

The sample consisted of 17 patients who underwent laparoscopic cholecystectomy for the treatment of cholelithiasis.

Nine patients used nicotine patch, and eight, placebo patch.

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

Because people in this Therapeutic nicotine (patch, non-peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Some patients received a placebo instead of Therapeutic nicotine (patch, non-peptide), giving a reference point.

The researchers conducted an analytical, prospective, randomized, triple-blinded, clinical study between January and July 2017.

What Was Measured

The subject headings attached to it are Analgesics, Opioid, Cholecystectomy, Laparoscopic, Hemodynamics, Morphine, Nausea, Pain Management and Postoperative Pain.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Therapeutic nicotine (patch, non-peptide) in 17 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2018 (Revista do Colegio Brasileiro de Cirurgioes), a journal based in Brazil.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.