Vitamin D Decreases Beck Depression Inventory Score in Patients with Mild to Moderate Ulcerative Colitis: A Double-Blind Randomized Placebo-Controlled Trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The aim of this study was to assess the effect of vitamin D on Beck Depression Inventory (BDI) score in ulcerative colitis (UC) patients.

Why It Was Studied

Some studies assessed the link between vitamin D and depression.

At baseline and 3 months later, measurements of BDI score and serum 25-OH-vitamin D3 were done.

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

Some studies assessed the link between vitamin D and depression.

At baseline and 3 months later, measurements of BDI score and serum 25-OH-vitamin D3 were done.

Topics PubMed links to this paper include Calcifediol, Cholecalciferol, Colitis, Ulcerative, Depression, Dietary Supplements and Vitamin D Deficiency.

The authors tagged it with the keywords BDI, IBD and ulcerative colitis.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2019 (Journal of dietary supplements), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.