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Effect of Vitamin D supplementation on body composition and cardiorespiratory fitness in overweight men-a randomized controlled trial.
Plain-language guide to PMID 29978375 (2018): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 29978375
- Journal
- Endocrine
- Year
- 2018
- Study type
- Randomized Controlled Trial
- Authors
- Karefylakis C et al. (6 authors)
- DOI
- 10.1007/s12020-018-1665-6
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
Only a few studies have examined the impact of vitamin D supplementation on these conditions and the results are ambiguous.
The aim of this study was to examine the effect of vitamin D supplementation on body composition and cardiorespiratory fitness in overweight/obese men with vitamin D deficiency.
Who Took Part
The age groups tagged for this paper are adults and middle-aged adults, men only.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
At baseline and follow up body composition and cardiorespiratory fitness were measured and blood samples were obtained.
Body composition was measured using bioelectrical impedance analysis (BIA) and cardiorespiratory fitness using cardiopulmonary exercise test (CPET).
The primary outcomes were changes in percentage body fat and in maximum oxygen uptake (VO2max).
What Was Measured
PubMed files the paper under topics including Body Composition, Cardiorespiratory Fitness, Dietary Supplements, Overweight and Vitamin D.
Author keywords: Bioelectrical impedance analysis and Cardiopulmonary exercise test.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2018 (Endocrine), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.