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Effect of Plasma Level of Vitamin D on Postoperative Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Grafting.

Plain-language guide to PMID 30043913 (2018): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 50 patients.

Key Facts

PMID
30043913
Journal
Brazilian journal of cardiovascular surgery
Year
2018
Study type
Randomized Controlled Trial
Authors
Özsin KK et al. (5 authors)
DOI
10.21470/1678-9741-2017-0214

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Postoperative atrial fibrillation (PoAF) is a common complication after coronary artery bypass grafting (CABG).

The aim of the present study was to evaluate the association between development of PoAF and vitamin D levels in patients undergoing isolated CABG.

Who Took Part

The study group was 50 patients.

PubMed indexes the participants as middle-aged adults and older adults, both men and women.

This prospective randomized clinical trial was conducted on the patients with isolated CABG.

The study was terminated when 50 patients in both PoAF(+) group and PoAF(-) group were reached.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Development of AF until discharge period was assessed.

Vitamin D level was measured immediately after AF; it was measured on the discharge day for the patients without PoAF.

Predictive values of the independent variables were measured for the development of PoAF.

What Was Measured

The subject headings attached to it are Age Factors, Atrial Fibrillation, Coronary Artery Bypass, Logistic Models, Multivariate Analysis, Postoperative Complications and Predictive Value of Tests.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 50 patients.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (Brazilian journal of cardiovascular surgery), a journal based in Brazil.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.