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Comparison the analgesic effect of magnesium sulphate and Ketorolac in the treatment of renal colic patients: Double-blind clinical trial study.

Plain-language guide to PMID 30172601 (2019): randomized and double-blind clinical trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
30172601
Journal
The American journal of emergency medicine
Year
2019
Study type
Clinical Trial
Authors
Maleki Verki M et al. (5 authors)
DOI
10.1016/j.ajem.2018.08.040

What This Study Did, in Plain Language

What Was Tested

This clinical trial looks at Vitamin D, K2, Magnesium and Zinc.

The researchers have aimed to evaluate the analgesic effects of magnesium sulphate on acute renal colic pain.

Why It Was Studied

Ureter muscles contraction movements caused pain in renal colic.

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

The pain severity of patients was assessed using the visual analog scale (VAS) at baseline, and 15 and 30 min after intervention.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

PubMed files the paper under topics including Analgesics, Analysis of Variance, Anti-Inflammatory Agents, Non-Steroidal, Ketorolac, Magnesium Sulfate, Pain and Pain Management.

Author keywords: Magnesium sulphate, Renal colic and Sedation.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2019 (The American journal of emergency medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.