Effect of Vitamin D Deficiency on Hypertrophic Scarring.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The authors aimed to determine the relationship between vitamin D deficiency and HS and investigate the effect of replacement therapy on HS development in patients with vitamin D deficiency.

Why It Was Studied

Although many different diseases have been reported with vitamin D deficiency, the authors failed to find any studies on the association of hypertrophic scarring (HS) in the literature.

Who Took Part

The study group was 50 patients.

By PubMed's age tags, the people studied were children, teenagers, adults and middle-aged adults, both men and women.

Patients who presented to the authors' outpatient clinic with HS between 2013 and 2016 were included in the study.

In the first stage, all the patients with HS complaints were assessed for vitamin D levels.

How the Study Was Run

The design is described as randomized.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Group 1: patients who did not accept any medical or surgical treatment; Group 2: patients who were subjected to vitamin D replacement only; Group 3: patients who underwent surgical excision and suturation after vitamin D replacement.

What Was Measured

PubMed files the paper under topics including Cicatrix, Hypertrophic, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 50 patients.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.