Efficacy of high zinc biofortified wheat in improvement of micronutrient status, and prevention of morbidity among preschool children and women - a double masked, randomized, controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Agronomic approaches such as application of Zn fertilizers to soil and/or foliar spray seem to be a practical tool for Zn biofortification of wheat.

Http://ctri.nic.in/Clinicaltrials/, CTRI/2014/04/004527, Registered April 7, 2014.

Who Took Part

According to the abstract, 6005 participants were involved.

PubMed indexes the participants as young children, children, teenagers, young adults, adults and middle-aged adults, both men and women.

How the Study Was Run

The design is described as randomized and double-blind.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Baseline and endline blood samples were obtained for assessing hematological markers; zinc status and data on compliance and morbidity were collected.

What Was Measured

PubMed files the paper under topics including Food, Fortified, India, Malnutrition, Micronutrients, Nutritional Status, Triticum and Zinc.

Author keywords: Biofortification, Children, Morbidity, Plasma zinc and Woman of child-bearing age.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 6005 participants.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2018 (Nutrition journal), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.