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Association of benign paroxysmal positional vertigo with vitamin D deficiency: a systematic review and meta-analysis.
Plain-language guide to PMID 30302575 (2018): meta-analysis of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 30302575
- Journal
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
- Year
- 2018
- Study type
- Meta-Analysis
- Authors
- AlGarni MA et al. (5 authors)
- DOI
- 10.1007/s00405-018-5146-6
What This Paper Covers, in Plain Language
What It Covers
This meta-analysis looks at Vitamin D, K2, Magnesium and Zinc.
Benign paroxysmal positional vertigo (BPPV) is an idiopathic recurrent inner ear illness that is caused most often by an imbalance in the metabolism of calcium carbonate crystals (otoconia) inside the semicircular canals, in which the otoconia begin to circulate freely after being dislodged from the basic structure.
The underlying etiology of this imbalance has not yet been well established; however, a few recent articles have revealed that vitamin D level abnormality in these patients might play a role.
Therefore, the researchers conducted the current systematic review analysis to explore potential associations of vitamin D level with the occurrence as well as the recurrence of BPPV disease.
How the Review Was Done
A comprehensive literature search was conducted using different databases to retrieve all of the articles that have evaluated possible associations, irrespective of the study design.
Then, the researchers reported different vitamin D3 levels from BPPV groups and control groups to estimate the standardized mean difference (SMD) between the BPPV and control groups.
The researchers also calculated the effect size of each study under the random effects statistical model.
What Was Measured
The subject headings attached to it are Benign Paroxysmal Positional Vertigo, Recurrence and Vitamin D Deficiency.
Author keywords: Benign positional paroxysmal vertigo, Meta-analysis and Systematic review.
What This Means in Plain Language
This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2018 (European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.