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Status of vitamin D and parameters of calcium homeostasis in renal transplant recipients in Nepal: a cross sectional study.
Plain-language guide to PMID 30348109 (2018): observational study of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 30348109
- Journal
- BMC nephrology
- Year
- 2018
- Study type
- Observational Study
- Authors
- Timalsina S et al. (4 authors)
- DOI
- 10.1186/s12882-018-1088-x
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.
This study aimed to determine the prevalence of hypovitaminosis D in Nepalese RTRs and interrelations between serum 25-hydroxyvitamin D [25(OH) D] and other biochemical parameters.
Appropriate statistical tests were applied to compare variables between groups and establish correlation.
Why It Was Studied
Vitamin D, apart from being an important part of the "calcium-vitamin D-parathyroid hormone" endocrine axis, has diverse range of "non-calcemic" biological actions.
A high prevalence of vitamin D deficiency has been observed in renal transplant recipients (RTRs) worldwide.
Who Took Part
By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.
A total of 80 adult RTRs visiting a university hospital were enrolled in this cross sectional study.
How the Study Was Run
Serum 25(OH) D and intact parathyroid hormone (iPTH) were measured using Enhanced Chemiluminiscent Immunoassay.
The RTR population was categorized into recent transplant recipients (≤1 year) and long term recipients (> 1 year).
The vitamin D status was defined as per NKF/KDOQI guidelines.
SPSS version 20.0 was used to analyze the data.
What Was Measured
Topics PubMed links to this paper include Calcium, Cross-Sectional Studies, Homeostasis, Kidney Transplantation, Nepal, Transplant Recipients and Vitamin D.
The authors tagged it with the keywords Hypovitaminosis D, Renal transplant recipients and Sensible sun exposure.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 10 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2018 (BMC nephrology), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.