Effect of Vitamin D Treatment on Glucose Homeostasis and Metabolism in Lebanese Older Adults: A Randomized Controlled Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Since age affect insulin sensitivity and the metabolism, the researchers aimed in this randomized controlled trial to investigate the effect of vitamin D supplementation on glucose homeostasis and index of insulin resistance in elderly subjects living in Beirut, Lebanon.

Who Took Part

PubMed indexes the participants as middle-aged adults and older adults, both men and women.

The index of insulin resistance HOMA (homeostasis model assessment) was the primary outcome.

Glucose homeostasis and metabolic markers were also measured at start of treatment and at 6 months.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

What Was Measured

Topics PubMed links to this paper include Aging, Blood Glucose, Homeostasis, Lebanon, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords HOMA-IR, HbA1c and insulin resistance.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2018 (The journal of nutrition, health & aging), a journal based in France.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.