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Complex assessment of patients with decompensated heart failure: The clinical value of impedance cardiography and N-terminal pro-brain natriuretic peptide
Plain-language guide to PMID 30391076 (2019): observational study of BNP (Nesiritide) in 102 patients.
Key Facts
- PMID
- 30391076
- Journal
- Heart & lung : the journal of critical care
- Year
- 2019
- Study type
- Observational Study
- Authors
- Galas A et al. (8 authors)
- DOI
- 10.1016/j.hrtlng.2018.10.004
What This Study Did, in Plain Language
What Was Tested
This observational study looks at BNP (Nesiritide).
The aim of this study was to evaluate the usefulness of ICG in the admission diagnostics and monitoring the effects of treatment in patients hospitalized due to ADHF, with special emphasis on its relation to NT-proBNP.
Why It Was Studied
Acute decompensated heart failure (ADHF) is a serious clinical problem and a condition requiring immediate diagnostics, supporting the therapeutic decision adequate to the specific ADHF mechanism.
N-terminal pro-brain natriuretic peptide (NT-proBNP) is an established biochemical marker of heart failure, strongly related to hemodynamic status.
Who Took Part
According to the abstract, 102 patients were involved.
By PubMed's age tags, the people studied were older adults, both men and women.
The subjects underwent detailed clinical assessment, including ICG and NT-proBNP at admission and at discharge day.
What Was Measured
Impedance cardiography (ICG) provides non-invasive hemodynamic assessment that can be performed immediately at the bedside and revealed to be useful diagnostic tool in some clinical settings in cardiology.
PubMed files the paper under topics including Acute Disease, Biomarkers, Blood Pressure, Cardiography, Impedance, Heart Failure, Heart Rate and Natriuretic Peptide, Brain.
Author keywords: Acute heart failure, Congestion, Hypervolemia, Impedance cardiography and Thoracic fluid content.
What This Means in Plain Language
This is an observational study of BNP (Nesiritide) in 102 patients.
Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2019 (Heart & lung : the journal of critical care), a journal based in United States.
More context: the BNP (Nesiritide) compound page, all human trials.
Our Notes on the Compound
BNP (Nesiritide): B-type natriuretic peptide, a 32-amino-acid heart hormone; nesiritide (Natrecor) is a recombinant form used in acute heart failure.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.