← Human Trials & Peer-Reviewed Studies
Effect of Vitamin D Therapy on Sexual Function in Women with Sexual Dysfunction and Vitamin D Deficiency: A Randomized, Double-Blind, Placebo Controlled Clinical Trial.
Plain-language guide to PMID 30395842 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc, sexual function & libido (women and men).
Key Facts
- PMID
- 30395842
- Journal
- The Journal of urology
- Year
- 2019
- Study type
- Randomized Controlled Trial
- Authors
- Jalali-Chimeh F et al. (7 authors)
- DOI
- 10.1016/j.juro.2018.10.019
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of sexual function & libido (women and men), published as a randomized controlled trial.
The researchers investigated the effect of vitamin D therapy on sexual function in women with low vitamin D levels and sexual dysfunction.
Who Took Part
PubMed indexes the participants as teenagers, young adults, adults and middle-aged adults, women only.
The researchers performed this randomized, double-blind, placebo controlled trial in women 18 to 45 years old with sexual dysfunction, defined as a FSFI (Female Sexual Functioning Index) score less than 26.55, and serum 25[OH]D less than 30 ng/ml.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
Sexual function was evaluated with the FSFI at baseline, and 4 and 8 weeks.
The serum level of 25[OH]D was measured and depression symptoms were evaluated by the BDI (Beck Depression Inventory) at baseline and 8 weeks.
What Was Measured
PubMed files the paper under topics including Dietary Supplements, Risk Assessment, Sexual Dysfunction, Physiological, Vitamin D and Vitamin D Deficiency.
The authors tagged it with the keywords depression, psychological, sexual dysfunctions and women's health.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in people with sexual function & libido (women and men).
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2019 (The Journal of urology), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, Sexual function & libido (women and men) research.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.