Effect of Monthly Vitamin D on Chronic Pain Among Community-Dwelling Seniors: A Randomized, Double-Blind Controlled Trial.

Plain-language guide to PMID 30401610 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc, chronic pain: fibromyalgia & crps.

Key Facts

PMID: 30401610
Journal: Journal of the American Medical Directors Association
Year: 2019
Study type: Randomized Controlled Trial
Authors: Schlögl M et al. (9 authors)
DOI: 10.1016/j.jamda.2018.09.004

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of chronic pain: fibromyalgia & crps in this randomized controlled trial publication.

Who Took Part

By PubMed's age tags, the people studied were older adults and people over 80, both men and women.

Participants were 200 community-dwelling men and women 70 years and older with a prior fall.

How the Study Was Run

In design terms this was a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

1-year, double-blind randomized clinical trial.

The trial was conducted in Zurich, Switzerland.

All analyses were adjusted for age, sex, body mass index, 25-hydroxyvitamin (OH)D3 levels, and pain scores at baseline.

A predefined subgroup analysis was performed by baseline 25(OH)D status (<20 vs ≥ 20 ng/mL).

What Was Measured

Topics PubMed links to this paper include Chronic Pain, Independent Living, Pain Measurement, Switzerland, Vitamin D, Vitamin D Deficiency and Vitamins.

The authors tagged it with the keywords McGill Pain map, Vitamin D supplementation, calcifediol, double-blind RCT and seniors.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in people with chronic pain: fibromyalgia & crps.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Journal of the American Medical Directors Association), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Chronic pain: fibromyalgia & CRPS research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.