[Effect of magnesium sulphate and milrinone on cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a randomized study].

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The aim of the present study was to compare the effect of prophylactic magnesium sulphate and milrinone on the incidence of cerebral vasospasm after subarachnoid hemorrhage.

Why It Was Studied

Milrinone is also used in the treatment of cerebral vasospasm.

Who Took Part

The study group was 90 patients.

PubMed indexes the participants as middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

What Was Measured

The subject headings attached to it are Calcium Channel Blockers, Incidence, Magnesium Sulfate, Milrinone, Phosphodiesterase 3 Inhibitors, Subarachnoid Hemorrhage and Vasospasm, Intracranial.

The authors tagged it with the keywords Aneurysmal subarachnoid hemorrhage, Cerebral vasospasm, Hemorragia subaracnoidea por aneurisma, Magnesium sulphate, Milrinona and Sulfato de magnésio.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 90 patients.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2019 (Brazilian journal of anesthesiology (Elsevier)), a journal based in Brazil.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.