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Physical Performance and Vitamin D in Elderly Black Women-The PODA Randomized Clinical Trial.
Plain-language guide to PMID 30496578 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 260 women.
Key Facts
- PMID
- 30496578
- Journal
- The Journal of clinical endocrinology and metabolism
- Year
- 2019
- Study type
- Randomized Controlled Trial
- Authors
- Aloia JF et al. (6 authors)
- DOI
- 10.1210/jc.2018-01418
- Registered trial
- NCT01153568
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
There is limited information on the influence of vitamin D on physical performance in black Americans.
Who Took Part
The study group was 260 women.
PubMed indexes the participants as middle-aged adults and older adults, women only.
The trial was 3 years in duration with measurement of physical performance every 6 months: grip strength, Short Physical Performance Battery (SPPB), 10 chair rises, and 6-minute walk distance.
A total of 260 women entered the study and 184 completed 3 years.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
The women were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Neither the women nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
Mean age was 68.2 years.
Research center in an academic health center.
Participants were randomly assigned to placebo or active vitamin D.
What Was Measured
The subject headings attached to it are Black or African American, Case-Control Studies, Cholecalciferol, Dietary Supplements, Osteoporosis, Physical Functional Performance and Prognosis.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 260 women.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2019 (The Journal of clinical endocrinology and metabolism), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.