Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a randomized controlled trial.

To study the effect of aging and granulosa cell growth hormone receptor (GHR) expression, and the effect of growth hormone (GH) co-treatment during IVF on receptor expression.

Who Took Part

According to the abstract, 62 women were involved.

The age groups tagged for this paper are young adults, adults and middle-aged adults, women only.

A total of 445 follicles were collected from 62 women undergoing standard infertility treatment.

How the Study Was Run

The design is described as randomized.

Because people in this Exogenous HGH, sermorelin & older GHRPs (why they're passed over) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Preovulatory ovarian follicle biopsies of granulosa cells and follicular fluid.

What Was Measured

PubMed files the paper under topics including Bone Morphogenetic Protein Receptors, Type I, Fertilization in Vitro, Granulosa Cells, Human Growth Hormone, Infertility, Female, Maternal Age and Ovarian Reserve.

The authors tagged it with the keywords Aging, pregnancy rate and receptor density.

What This Means in Plain Language

The paper is a randomized study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 62 women.

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2018 (Fertility and sterility), a journal based in United States.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.