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Cross-sectional associations of vitamin D status with asthma prevalence, exacerbations, and control in New Zealand adults.

Plain-language guide to PMID 30508643 (2019): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 5110 participants.

Key Facts

PMID
30508643
Journal
The Journal of steroid biochemistry and molecular biology
Year
2019
Study type
Randomized Controlled Trial
Authors
Win SS et al. (8 authors)
DOI
10.1016/j.jsbmb.2018.11.016

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Previous studies, mostly with children, have reported inconsistent findings on the associations of vitamin D status with asthma prevalence, exacerbations, and control.

Who Took Part

The abstract describes 5110 participants taking part.

By PubMed's age tags, the people studied were middle-aged adults, older adults and people over 80, both men and women.

5110 participants, aged 50-84 years, were recruited from the community into a clinical trial of vitamin D supplementation.

The current analysis is based on baseline blood sample collection to measure serum 25-hydroxyvitamin D (25(OH)D), which was deseasonalized for data analyses; and baseline asthma assessment, which included questions on asthma prevalence, urgent medical care for asthma in the previous 12 months, and control of asthma symptoms in the previous 4 weeks.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

The subject headings attached to it are Ambulatory Care, Asthma, Cross-Sectional Studies, Prevalence, Vitamin D, Vitamin D Deficiency and Vitamins.

The authors tagged it with the keywords 25-Hydroxyvitamin D, Asthma control, Asthma exacerbations and Cross-sectional survey.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 5110 participants.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (The Journal of steroid biochemistry and molecular biology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.