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Comparing Vitamin D Supplementation Versus Placebo for Urgency Urinary Incontinence: A Pilot Study.

Plain-language guide to PMID 30578542 (2019): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
30578542
Journal
Journal of the American Geriatrics Society
Year
2019
Study type
Randomized Controlled Trial
Authors
Markland AD et al. (7 authors)
DOI
10.1111/jgs.15711
Registered trial
NCT01971801

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Who Took Part

PubMed indexes the participants as middle-aged adults and older adults, women only.

Community-dwelling postmenopausal women, 50 years or older, with at least three UUI episodes on 7-day bladder diary and serum vitamin 25-hydroxyvitamin D (25[OH]D) of 30 ng/mL or less.

How the Study Was Run

The researchers set it up as a randomized, placebo-controlled and pilot study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

Pilot, two-arm, randomized trial conducted from 2013 to 2017.

Secondary estimates included changes in other lower urinary tract symptoms, along with exploratory subgroup analysis by race/ethnicity and obesity.

What Was Measured

The subject headings attached to it are Dietary Supplements, Independent Living, Medical Records, Pilot Projects, Postmenopause, Risk Factors and Symptom Assessment.

The authors tagged it with the keywords postmenopausal women, urinary incontinence and vitamin D.

What This Means in Plain Language

The paper is a randomized, placebo-controlled and pilot study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 9 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Journal of the American Geriatrics Society), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.