Effects of Daily Zinc, Daily Multiple Micronutrient Powder, or Therapeutic Zinc Supplementation for Diarrhea Prevention on Physical Growth, Anemia, and Micronutrient Status in Rural Laotian Children: A Randomized Controlled Trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of anemia in this randomized controlled trial publication.

Who Took Part

The study group was 3407 children.

The age groups tagged for this paper are infants.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the children and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

Anthropometry, hemoglobin, zinc, and iron status were assessed at baseline and endline.

Analyses were by intention-to-treat, using linear and modified Poisson regression.

What Was Measured

The subject headings attached to it are Anemia, Iron-Deficiency, Diarrhea, Dietary Supplements, Growth Disorders, Laos, Micronutrients and Powders.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 3407 children in people with anemia.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (The Journal of pediatrics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Anemia research.