A Clinical Investigation of a Dual Zinc plus Arginine Dentifrice in Reducing Established Dental Plaque and Gingivitis Over a Six-Month Period of Product Use.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Who Took Part

The age groups tagged for this paper are adults, both men and women.

A total of 100 adult male and female subjects from Santo Domingo, Dominican Republic were enrolled in this clinical study.

The examining clinician also performed an assessment of the oral soft and hard tissues.

How the Study Was Run

In design terms this was a randomized, double-blind and parallel-group study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

During the baseline visit, the dental examiner clinically measured three gingival parameters (gingival index, gingival severity index, gingival interproximal index) and three plaque parameters (plaque index, plaque severity index, plaque interproximal index).

All subjects were then assigned a subject identification number in chronological order from 001 to 100 and were randomly assigned to one of two treatment groups following a computer-generated randomization list.

Subjects returned to the study facility site for their follow-up evaluation of plaque and gingivitis parameters after three and six months.

What Was Measured

PubMed files the paper under topics including Arginine, Dental Plaque, Dental Plaque Index, Dentifrices, Gingivitis, Periodontal Index and Zinc.

Author keywords: clinical study.

What This Means in Plain Language

The paper is a randomized, double-blind and parallel-group study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (The Journal of clinical dentistry), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.