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Zinc Absorption from Micronutrient Powders Is Low in Bangladeshi Toddlers at Risk of Environmental Enteric Dysfunction and May Increase Dietary Zinc Requirements.

Plain-language guide to PMID 30624753 (2019): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 10 subjects.

Key Facts

PMID
30624753
Journal
The Journal of nutrition
Year
2019
Study type
Randomized Controlled Trial
Authors
Long JM et al. (9 authors)
DOI
10.1093/jn/nxy245
Registered trial
NCT02758444

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Environmental enteric dysfunction (EED), a chronic inflammatory disorder of the small bowel, is suspected to impair absorption of micronutrients, including zinc.

Who Took Part

The abstract describes 10 subjects taking part.

The age groups tagged for this paper are infants and young children, both men and women.

Secondary outcomes included investigation of relations of TAZ to intake, to physiologic requirement, and to other variables, including biomarkers of systemic and intestinal inflammation, using nonlinear models.

TAZ was also compared with published data on child zinc absorption.

How the Study Was Run

The researchers set it up as a randomized study.

The subjects were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

What Was Measured

PubMed files the paper under topics including Bangladesh, Biological Transport, Child Nutritional Physiological Phenomena, Dietary Supplements, Micronutrients, Nutritional Requirements and Nutritional Status.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 10 subjects.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (The Journal of nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.