Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The aim of the study was to assess the analgesic effect of magnesium sulfate when used as an adjuvant in prehospital FNB.

Who Took Part

PubMed indexes the participants as middle-aged adults, older adults and people over 80, both men and women.

This is a randomized double-blinded trial conducted in a prehospital medical department of an academic hospital.

Patients with isolated diaphysial femoral fracture and eligible to participate were randomized into 2 groups.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The FNB was performed according to the WINNIE technique.

Primary endpoints were morphine consumption and pain intensity during the first 6 hours.

Secondary endpoints were the duration of the sensory block, time to the first analgesic request, and side effects occurrence.

What Was Measured

Topics PubMed links to this paper include Analgesics, Opioid, Anesthesia, Local, Anesthetics, Local, Femoral Fractures, Femoral Nerve, Lidocaine and Magnesium Sulfate.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2018 (Pain research & management), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.