Effect of combined vitamin D administration plus dietary intervention on oxidative stress markers in patients with metabolic syndrome: A pilot randomized study.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

To study the effect of 25(OH)VitD administration plus dietary intervention on oxidative stress markers in MetS patients.

Why It Was Studied

There is little data on the effect of 25(OH)VitD administration plus dietary intervention on oxidative stress markers in these patients.

Who Took Part

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

(Suppl group) or no supplementation (No-Suppl group).

How the Study Was Run

The researchers set it up as a randomized and pilot study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

This is a pre-specified analysis of a previously published study (NCT01237769 ClinicalTrials.gov).

What Was Measured

PubMed files the paper under topics including Aryldialkylphosphatase, Biomarkers, Carboxylic Ester Hydrolases, Combined Modality Therapy, Dietary Supplements, Dinoprost and Greece.

The authors tagged it with the keywords Metabolic syndrome, Oxidative stress and Vitamin D.

What This Means in Plain Language

The paper is a randomized and pilot study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Clinical nutrition ESPEN), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.