Vitamin D insufficiency and deficiency are associated with a higher level of serum uric acid: A systematic review and meta-analysis.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this meta-analysis publication.

The current systematic review and meta-analysis was conducted with the aim to summarize all the available data.Methods: A systematic review was conducted using MEDLINE and EMBASE database from inception to May 2018 to identify all studies that compared the level of serum uric acid between individuals with normal vitamin D level and patients with vitamin D insufficiency/deficiency.

Why It Was Studied

Eligible studies must be cohort or cross-sectional studies that consisted of two groups of adult participants, one with normal level of vitamin D (vitamin D level >30 ng/ml) and one with vitamin D insufficiency (vitamin D level 20-30 ng/ml) or vitamin D deficiency (vitamin D level of <20 ng/ml).

Mean serum uric acid level and standard deviation of participants were extracted from each study to calculate mean difference (MD).

What Was Measured

Eligible studies must be cohort or cross-sectional studies that consisted of two groups of adult participants, one with normal level of vitamin D (vitamin D level >30 ng/ml) and one with vitamin D insufficiency (vitamin D level 20-30 ng/ml) or vitamin D deficiency (vitamin D level of <20 ng/ml).

Mean serum uric acid level and standard deviation of participants were extracted from each study to calculate mean difference (MD).

The subject headings attached to it are Biomarkers, Uric Acid and Vitamin D Deficiency.

The authors tagged it with the keywords hyperuricemia, meta-analysis and vitamin D insufficiency.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2020 (Modern rheumatology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.