The effects of magnesium and vitamin E co-supplementation on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

This study was carried out to determine the effects of magnesium and vitamin E co-supplementation on wound healing and metabolic status in patients with diabetic foot ulcer (DFU).

Why It Was Studied

The current randomized, double-blind, placebo-controlled trial was conducted among 57 patients with grade 3 DFU.

Who Took Part

The study group was 57 patients.

The age groups tagged for this paper are adults, middle-aged adults, older adults and people over 80, both men and women.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Some patients received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

The subject headings attached to it are Antioxidants, Diabetic Foot, Dietary Supplements, Magnesium, Oxidative Stress, Vitamin E and Wound Healing.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 57 patients.

The publication is from 2019 (Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.