Clinical Effect of Low Molecular Weight Heparin Sodium Combined with Magnesium Sulfate in the Treatment of Patients with Severe Preeclampsia.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To investigate the effect of low molecular weight heparin sodium combined with magnesium sulfate in the treatment of patients with severe preeclampsia.

Why It Was Studied

The Department of Obstetrics and Gynecology, The Affiliated Hospital, North China University of Science and Technology, from April 2016 to July 2017.

Who Took Part

By PubMed's age tags, the people studied were adults, women only.

Patients with severe preeclampsia were randomly divided into observation group (52 cases) and control group (51 cases).

After treatment of 7 days, serum TGF-β1, VCAM-1, ES levels and endothelial function markers of NO and ET-1 changes were compared between the two groups.The delivery status after treatment was observed in both groups.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

In the control group, magnesium sulfate were used, but in observation group low molecular weight heparin sodium were added.

What Was Measured

Topics PubMed links to this paper include Heparin, Low-Molecular-Weight, Magnesium Sulfate, Pre-Eclampsia and Pregnancy Outcome.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Journal of the College of Physicians and Surgeons--Pakistan : JCPSP), a journal based in Pakistan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.