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Racial/Ethnic Differences in 25-Hydroxy Vitamin D and Parathyroid Hormone Levels and Cardiovascular Disease Risk Among Postmenopausal Women
Plain-language guide to PMID 30764690 (2019): observational study study of Parathyroid Hormone (PTH 1-84) in 79,705 women.
Key Facts
- PMID
- 30764690
- Journal
- Journal of the American Heart Association
- Year
- 2019
- Study type
- Observational Study
- Authors
- Zhang X et al. (11 authors)
- DOI
- 10.1161/JAHA.118.011021
What This Study Did, in Plain Language
What Was Tested
This observational study paper looks at Parathyroid Hormone (PTH 1-84).
Methods and Results the researchers conducted a case-cohort study among 79 705 postmenopausal women, aged 50 to 79 years, who were free of CVD at baseline in the WHI-OS (Women's Health Initiative Observational Study).
A subcohort of 1300 black and 1500 white participants were randomly chosen as controls; a total of 550 black and 1500 white women who developed incident CVD during a mean follow-up of 11 years were chosen as cases.
Who Took Part
The abstract describes 79,705 women taking part.
By PubMed's age tags, the people studied were middle-aged adults and older adults, women only.
What Was Measured
The researchers directly measured total 25( OH )D, vitamin D-binding protein, albumin, parathyroid hormone, and calculated free and bioavailable 25( OH )D.
PubMed files the paper under topics including Biomarkers, Cardiovascular Diseases, Case-Control Studies, Ethnicity, Forecasting, Incidence and Parathyroid Hormone.
The authors tagged it with the keywords 25(OH)D, parathyroid hormone/calcitonin, vitamin D and women.
What This Means in Plain Language
This is an observational study of Parathyroid Hormone (PTH 1-84) in 79,705 women.
The publication is from 2019 (Journal of the American Heart Association), a journal based in England.
More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.
Our Notes on the Compound
Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.