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Central precocious puberty in girls: Diagnostic study and auxological response to triptorelin treatment
Plain-language guide to PMID 30808564 (2019): observational study of Triptorelin in 60 girls.
Key Facts
- PMID
- 30808564
- Journal
- Endocrinologia, diabetes y nutricion
- Year
- 2019
- Study type
- Observational Study
- Authors
- Durá-Travé T et al. (6 authors)
- DOI
- 10.1016/j.endinu.2018.12.007
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Triptorelin, published as an observational study.
The aim of this study is to present the experience acquired in a group of girls with CPP treated with triptorelin, and to analyze the auxological characteristics and diagnostic tests.
Why It Was Studied
There are several controversies regarding the diagnostic tests and management of central precocious puberty (CPP).
Who Took Part
According to the abstract, 60 girls were involved.
By PubMed's age tags, the people studied were children, women only.
Girls were treated with triptorelin and monitored after treatment discontinuation until menarche.
How the Study Was Run
An observational, retrospective study in a group of 60 girls with CPP was conducted between January 2010 and December 2017.
Sociodemographic, auxological and hormonal data were recorded at diagnosis, and pelvic ultrasound and magnetic resonance imaging of the head were performed.
What Was Measured
There are several controversies regarding the diagnostic tests and management of central precocious puberty (CPP).
Topics PubMed links to this paper include Age Determination by Skeleton, Anthropometry, Estradiol, Follicle Stimulating Hormone, Luteinizing Hormone, Magnetic Resonance Imaging and Organ Size.
The authors tagged it with the keywords Análogos de hormona liberadora de gonadotropinas, Auxological characteristics, Central precocious puberty, Estudio auxológico, Gonadotropin-releasing hormone analogues and Pubertad precoz central.
What This Means in Plain Language
This is an observational study of Triptorelin in 60 girls.
The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2019 (Endocrinologia, diabetes y nutricion), a journal based in Spain.
More context: the Triptorelin compound page, all human trials.
Our Notes on the Compound
Triptorelin: A 10-amino-acid GnRH analog (Trelstar, Decapeptyl, Triptodur) used in prostate cancer, early puberty and fertility protocols.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.