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Central precocious puberty in girls: Diagnostic study and auxological response to triptorelin treatment

Plain-language guide to PMID 30808564 (2019): observational study of Triptorelin in 60 girls.

Key Facts

PMID
30808564
Journal
Endocrinologia, diabetes y nutricion
Year
2019
Study type
Observational Study
Authors
Durá-Travé T et al. (6 authors)
DOI
10.1016/j.endinu.2018.12.007

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Triptorelin, published as an observational study.

The aim of this study is to present the experience acquired in a group of girls with CPP treated with triptorelin, and to analyze the auxological characteristics and diagnostic tests.

Why It Was Studied

There are several controversies regarding the diagnostic tests and management of central precocious puberty (CPP).

Who Took Part

According to the abstract, 60 girls were involved.

By PubMed's age tags, the people studied were children, women only.

Girls were treated with triptorelin and monitored after treatment discontinuation until menarche.

How the Study Was Run

An observational, retrospective study in a group of 60 girls with CPP was conducted between January 2010 and December 2017.

Sociodemographic, auxological and hormonal data were recorded at diagnosis, and pelvic ultrasound and magnetic resonance imaging of the head were performed.

What Was Measured

There are several controversies regarding the diagnostic tests and management of central precocious puberty (CPP).

Topics PubMed links to this paper include Age Determination by Skeleton, Anthropometry, Estradiol, Follicle Stimulating Hormone, Luteinizing Hormone, Magnetic Resonance Imaging and Organ Size.

The authors tagged it with the keywords Análogos de hormona liberadora de gonadotropinas, Auxological characteristics, Central precocious puberty, Estudio auxológico, Gonadotropin-releasing hormone analogues and Pubertad precoz central.

What This Means in Plain Language

This is an observational study of Triptorelin in 60 girls.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Endocrinologia, diabetes y nutricion), a journal based in Spain.

More context: the Triptorelin compound page, all human trials.

Our Notes on the Compound

Triptorelin: A 10-amino-acid GnRH analog (Trelstar, Decapeptyl, Triptodur) used in prostate cancer, early puberty and fertility protocols.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.