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The effects of two vitamin D regimens on ulcerative colitis activity index, quality of life and oxidant/anti-oxidant status.

Plain-language guide to PMID 30871542 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 50 patients.

Key Facts

PMID
30871542
Journal
Nutrition journal
Year
2019
Study type
Randomized Controlled Trial
Authors
Karimi S et al. (7 authors)
DOI
10.1186/s12937-019-0441-7

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The aim of this study was to investigate the effects of two vitamin D regimens in UC patients with vitamin D deficiency.

Who Took Part

According to the abstract, 50 patients were involved.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Serum 25-hydroxy vitamin D (25-OHD) level, total antioxidant capacity (TAC), and Total Oxidant Status (TOS), the inflammatory bowel disease questionnaire - 9 (IBDQ-9) score and the Simple Clinical Colitis Activity Index Questionnaire (SCCAI) score were assessed before and after intervention.

What Was Measured

PubMed files the paper under topics including Antioxidants, Colitis, Ulcerative, Dietary Supplements, Iran, Oxidants, Oxidative Stress and Quality of Life.

Author keywords: Inflammatory bowel disease, Ulcerative colitis and Vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 50 patients.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2019 (Nutrition journal), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.