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A randomised controlled trial comparing the efficacy of micellised and fat-soluble vitamin D3 supplementation in healthy adults.

Plain-language guide to PMID 30898175 (2019): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in 180 adults.

Key Facts

PMID
30898175
Journal
The British journal of nutrition
Year
2019
Study type
Randomized Controlled Trial
Authors
Marwaha RK et al. (12 authors)
DOI
10.1017/S0007114518003215

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.

The outcome parameters were serum 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), Ca, phosphate, alkaline phosphatase and urinary Ca:creatinine ratio.

A total of eighty-nine subjects in group A and seventy-seven in group B completed the trial.

Who Took Part

The study group was 180 adults.

By PubMed's age tags, the people studied were young adults, adults and middle-aged adults, both men and women.

How the Study Was Run

In design terms this was a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

The outcome parameters were serum 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), Ca, phosphate, alkaline phosphatase and urinary Ca:creatinine ratio.

Topics PubMed links to this paper include Body Mass Index, Calcifediol, Cholecalciferol, Dietary Supplements, Drug Carriers, Healthy Volunteers and India.

Author keywords: 25(OH)D 25-hydroxyvitamin D, PTH parathyroid hormone, Adults, Conventional vitamin D, Micellised vitamin D3 and Randomised study.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in 180 adults.

The publication is from 2019 (The British journal of nutrition), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Parathyroid Hormone (PTH 1-84) compound page, all human trials.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.