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Exposure to a slightly sweet lipid-based nutrient supplement during early life does not increase the level of sweet taste most preferred among 4- to 6-year-old Ghanaian children: follow-up of a randomized controlled trial.

Plain-language guide to PMID 30915467 (2019): randomized controlled trial of Copper (Supplement).

Key Facts

PMID
30915467
Journal
The American journal of clinical nutrition
Year
2019
Study type
Randomized Controlled Trial
Authors
Okronipa H et al. (11 authors)
DOI
10.1093/ajcn/nqy352
Registered trial
NCT00970866

What This Study Did, in Plain Language

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

The researchers tested the hypothesis that the level of sucrose most preferred by 4-6-y-old children exposed to a slightly sweet lipid-based nutrient supplement (LNS) early in life would not be higher than that of children never exposed to LNS.

At age 4-6 y, the researchers randomly selected a subsample of children (n = 775) to assess the concentration of sucrose most preferred using the Monell 2-series, forced-choice, paired-comparison tracking procedure.

Why It Was Studied

The impact of feeding a slightly sweet nutrient supplement early in life on later sweet taste preference is unknown.

Who Took Part

The age groups tagged for this paper are infants, young children and children, both men and women.

The researchers followed up children born to women (n = 1,320) who participated in a randomized trial in Ghana.

How the Study Was Run

In design terms this was a randomized study.

Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.

What Was Measured

PubMed files the paper under topics including Food Preferences, Ghana, Infant Food, Lipid Metabolism, Nutrients, Sucrose and Taste.

The authors tagged it with the keywords Monell forced-choice test, children, lipid-based nutrient supplement and sweet taste preference.

What This Means in Plain Language

The paper is a randomized study of Copper (Supplement).

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2019 (The American journal of clinical nutrition), a journal based in United States.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.