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Infection Status of Rural Schoolchildren and its Relationship with Vitamin D Concentrations.

Plain-language guide to PMID 30915647 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 387 children.

Key Facts

PMID
30915647
Journal
Indian journal of pediatrics
Year
2019
Study type
Randomized Controlled Trial
Authors
Mandlik R et al. (5 authors)
DOI
10.1007/s12098-019-02933-4

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To assess the nutritional and infection status of rural schoolchildren and to study the relationship of infection status with serum 25(OH)D concentrations.

Who Took Part

The study group was 387 children.

PubMed indexes the participants as children, both men and women.

Data collected from 387 children included anthropometric, clinical, infection-related data (using a validated questionnaire) and dietary data (by 24-h recall method over 3 non-consecutive days, including a holiday) and serum 25(OH)D estimations (by ELISA).

How the Study Was Run

The design is described as randomized and double-blind.

The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the children and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

This study was carried out in a primary school, in a rural setting, near Pune (18°N), Maharashtra.

What Was Measured

PubMed files the paper under topics including Anthropometry, Cross-Sectional Studies, India, Nutrition Disorders, Nutritional Status, Prevalence and Respiratory Tract Infections.

Author keywords: 25(OH)D, Vitamin D status and Vitamin D sufficient, Vitamin D insufficient.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 387 children.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Indian journal of pediatrics), a journal based in India.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.