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The effect of perioperative magnesium sulfate on blood sugar in patients with diabetes mellitus undergoing cardiac surgery: A double-blinded randomized study.
Plain-language guide to PMID 30971596 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 122 patients.
Key Facts
- PMID
- 30971596
- Journal
- Annals of cardiac anaesthesia
- Year
- 2019
- Study type
- Randomized Controlled Trial
- Authors
- Soliman R et al. (2 authors)
- DOI
- 10.4103/aca.ACA_32_18
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
The aim of the present study was to evaluate the perioperative effect of magnesium infusion on blood sugar level in patients with diabetes mellitus undergoing cardiac surgery.
Who Took Part
The study group was 122 patients.
PubMed indexes the participants as middle-aged adults, both men and women.
The study included 122 adult patients.
Group C - The patients received equal amount of normal saline.
How the Study Was Run
The researchers set it up as a randomized and double-blind study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
This was a double-blind randomized study.
The study was conducted at cardiac center.
The infusion rate was started 20 min before induction maintained during surgery and the first postoperative 24 h.
The monitors included heart rate, mean arterial blood pressure, central venous pressure, urine output, blood levels of magnesium, sugar, and potassium.
What Was Measured
PubMed files the paper under topics including Blood Glucose, Calcium Channel Blockers, Cardiac Surgical Procedures, Diabetes Mellitus, Magnesium Sulfate and Perioperative Care.
The authors tagged it with the keywords Blood sugar, cardiac surgery, insulin and potassium.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 122 patients.
Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2019 (Annals of cardiac anaesthesia), a journal based in India.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.