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The Effect of Vitamin D on Serum Asymmetric Dimethylarginine in Patients with Mild to Moderate Ulcerative Colitis.
Plain-language guide to PMID 30982443 (2020): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 86 participants.
Key Facts
- PMID
- 30982443
- Journal
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- Year
- 2020
- Study type
- Randomized Controlled Trial
- Authors
- Javad Hosseinzadeh-Attar M et al. (5 authors)
- DOI
- 10.1024/0300-9831/a000303
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The aim of this study is to investigate the possible effect of Vitamin D3 on serum ADMA levels in ulcerative colitis (UC) patients.
Why It Was Studied
At baseline and 90 days after the intervention measurements were done.
Data were analyzed using independent t-test and analysis of covariance.
Who Took Part
The abstract describes 86 participants taking part.
Methods: Ninety mild to moderate UC patients were randomized.
How the Study Was Run
The design is described as randomized and placebo-controlled.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
Baseline correlations were assessed by Pearson and Spearman correlation coefficients.
What Was Measured
At baseline and 90 days after the intervention measurements were done.
Data were analyzed using independent t-test and analysis of covariance.
Topics PubMed links to this paper include Arginine, Colitis, Ulcerative, Vitamin D and Vitamins.
The authors tagged it with the keywords Asymmetric dimethylarginine, inflammatory bowel diseases and ulcerative colitis.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 86 participants.
The publication is from 2020 (International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition), a journal based in Singapore.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.