Can we use magnesium for sedation in the intensive care unit for critically ill patients: Is it as effective as other sedatives?

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The aim of this prospective, randomized study was to investigate the effect of magnesium added to midazolam on the hemodynamics, transition time to a T-piece, mechanical ventilation duration, additional sedative-analgesic requirement using bispectral index (BIS) monitorization and sedation scales.

Who Took Part

By PubMed's age tags, the people studied were teenagers, young adults, adults, middle-aged adults, older adults and people over 80, both men and women.

Fifty critically ill patients receiving mechanical ventilation support in the intensive care unit were randomly assigned to 2 groups.

How the Study Was Run

The design is described as randomized.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

BIS levels and sedation levels were continuously monitored.

What Was Measured

The subject headings attached to it are Procedural Sedation, Critical Illness, Hypnotics and Sedatives, Intensive Care Units, Magnesium, Midazolam and Pain Measurement.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology), a journal based in Turkey.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.