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Optimal sunscreen use, during a sun holiday with a very high ultraviolet index, allows vitamin D synthesis without sunburn.
Plain-language guide to PMID 31069787 (2019): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 31069787
- Journal
- The British journal of dermatology
- Year
- 2019
- Study type
- Randomized Controlled Trial
- Authors
- Young AR et al. (13 authors)
- DOI
- 10.1111/bjd.17888
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
To assess the ability of two intervention sunscreens to inhibit vitamin D synthesis during a week-long sun holiday.
Why It Was Studied
Sunlight contains ultraviolet (UV)A and UVB radiation.
UVB is essential for vitamin D synthesis but is the main cause of sunburn and skin cancer.
Who Took Part
The age groups tagged for this paper are adults and middle-aged adults, both men and women.
Healthy Polish volunteers (n = 20 per group) were given the sunscreens and advised on the correct application.
How the Study Was Run
The design is described as randomized.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Comparisons were made between two formulations, each with a sun protection factor (SPF) of 15.
The UVA-protection factor (PF) was low in one case and high in the other.
Comparisons were also made with discretionary sunscreen use (n = 22) and nonholiday groups (51·8° N, n = 17).
Sunscreen use in the intervention groups was measured.
Behaviour, UV radiation exposure, clothing cover and sunburn were monitored.
What Was Measured
Serum 25-hydroxyvitamin D3 [25(OH)D3 ] was assessed by high-performance liquid chromatography-tandem mass spectrometry.
The subject headings attached to it are Administration, Cutaneous, Calcifediol, Healthy Volunteers, Holidays, Poland, Skin and Skin Neoplasms.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 15 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2019 (The British journal of dermatology), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.