First Report of Edge Vascular Response at 12 Months of Magmaris, A Second-Generation Drug-Eluting Resorbable Magnesium Scaffold, Assessed by Grayscale Intravascular Ultrasound, Virtual Histology, and Optical Coherence Tomography. A Biosolve-II Trial Sub-Study.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical trial.

The edge vascular response (EVR) remains unknown in second generation drug-eluting Resorbable Magnesium Scaffold (RMS), such as Magmaris.

The aim of the study was to evaluate tissue modifications in the RMS edges over time, assessed by different invasive imaging modalities.

Why It Was Studied

The edge vascular response (EVR) remains unknown in second generation drug-eluting absorbable metal scaffolds (RMS), such as Magmaris.

Who Took Part

By PubMed's age tags, the people studied were young adults, adults, middle-aged adults and older adults.

The patients treated with the device were assessed by optical coherence tomography (OCT), grayscale intravascular ultrasound (IVUS), and virtual histology IVUS at baseline and 12 months.

The EVR study performed a segment- and frame-level analysis of the 5 mm segments proximal and distal of the actual RMS.

How the Study Was Run

Patients treated with the device were assessed by multi invasive imaging modalities [i.e. optical coherence tomography (OCT), grayscale intravascular ultrasound (IVUS), and virtual histology IVUS] evaluating the tissue changes over time in the segment- and frame-level analysis of the 5 mm segments proximal and distal of the actual RMS.

What Was Measured

The subject headings attached to it are Absorbable Implants, Angioplasty, Balloon, Coronary, Coronary Artery Disease, Drug-Eluting Stents, Fibrosis, Magnesium and Plaque, Atherosclerotic.

Author keywords: Edge vascular response, Grayscale intravascular ultrasound, Magmaris, Optical coherence tomography and Virtual histology.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Cardiovascular revascularization medicine : including molecular interventions), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.