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The Novel Effects of a Hydrolyzed Polysaccharide Dietary Supplement on Immune, Hepatic, and Renal Function in Adults with HIV in a Randomized, Double-Blind, Placebo-Control Trial.
Plain-language guide to PMID 31146613 (2020): double-blind randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 31146613
- Journal
- Journal of dietary supplements
- Year
- 2020
- Study type
- Randomized Controlled Trial
- Authors
- Lewis JE et al. (17 authors)
- DOI
- 10.1080/19390211.2019.1619010
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Copper (Supplement).
The primary objective of the study was to evaluate the effects of a hydrolyzed polysaccharide, rice bran arabinoxylan compound (RBAC), on immune, hepatic, and renal function in HIV + individuals.
Why It Was Studied
A 6-month randomized double-blind placebo-controlled trial was utilized to conduct the intervention.
No side effects were reported, and liver and kidney markers remained nearly completely within normal limits.
Who Took Part
By PubMed's age tags, the people studied were teenagers, young adults, adults, middle-aged adults and older adults, both men and women.
Participants were assessed at baseline and 3 and 6 months follow-up for CD4+ and CD8+, liver enzymes, and kidney function.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Neither the participants nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.
Some participants received a placebo instead of Copper (Supplement), giving a reference point.
What Was Measured
The subject headings attached to it are CD4-CD8 Ratio, Dietary Supplements, Glucans, HIV Infections, Kidney Function Tests, Liver Function Tests and Xylans.
The authors tagged it with the keywords CD4–CD8 ratio, arabinoxylan, immune system phenomena and polysaccharides.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).
The publication is from 2020 (Journal of dietary supplements), a journal based in England.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.