Time to treatment response of a magnesium- and sulphate-rich natural mineral water in functional constipation.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

First-line recommendations for the management of functional constipation include nutritional-hygienic measures.

The aim of this study was to consolidate those first results and determine a precise time to respond to Hépar.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, both men and women.

This multicenter, randomized, double-blind, controlled study of the effect of Hépar on stool consistency and frequency in functional constipation included 226 outpatients.

How the Study Was Run

The researchers set it up as a randomized, double-blind and multicenter study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Running at several centres spread the Vitamin D, K2, Magnesium and Zinc study over different clinics and patient groups.

What Was Measured

Topics PubMed links to this paper include Constipation, Feces, Magnesium, Mineral Waters, Minerals, Sulfates and Time-to-Treatment.

Author keywords: Bowel movement, Clinical trial, Functional constipation and Natural mineral water.

What This Means in Plain Language

The paper is a randomized, double-blind and multicenter study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Nutrition (Burbank, Los Angeles County, Calif.)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.